Is primary cold agglutinin disease a constant presence in your life?

If you're ready to learn about a potential new option for your condition, the CAD Studies may be of interest to you.

We are looking for adults aged 18 and older with primary cold agglutinin disease (also known as CAD or CagD) to take part in a clinical research study – as part of the CAD Studies. If you qualify for the CAD Studies, you may be enrolled into either the Cardinal Study or the Cadenza Study based on your medical history. The purpose of the CAD Studies is to determine the safety and effectiveness of an investigational medication for primary CAgD. The CAD Studies may be appropriate for those who meet the following criteria:

  • Males and females 18 years of age or older
  • Those who have a confirmed diagnosis of primary cold agglutinin disease
  • Both those who have had a blood transfusion in the last six months and those who have not

Find a participating research site.

To see if you may qualify, contact a participating research site below:

Dr. Sanjeev Chunilal

Monash Medical Centre

246 Clayton Road

Melbourne, VIC 3168

Get directions

Understanding primary cold agglutinin disease.

Primary CAgD is a type of autoimmune haemolytic anaemia in which the body’s immune system mistakenly attacks and destroys its own red blood cells. All primary CAgD patients have triggers that may make the symptoms worse, such as infection, changes in the weather or even reaching into a freezer at the supermarket. And it’s a very rare condition. It’s so rare that scientists estimate that only 16 people per million have the disease worldwide.1


What you should know about clinical research studies.

What is a clinical research study?

A clinical research study, also known as a clinical research trial, is a carefully designed study in which participants are asked to take an investigational medication under the supervision of a doctor and other research professionals.

Clinical research studies must be reviewed by an institutional review board (IRB) or ethics committee (EC). An IRB or EC is a group that is responsible for helping to protect the rights and welfare of study participants. In addition, every study participant is monitored with medical tests and study-related exams before, during and sometimes even after the study.

What is an investigational medication?

An investigational medication is a medicine that has not been approved by the regulatory authorities in your country.